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Dr. Subhadip Senapati

Senior Researcher (Chemistry)

Education

• Ph.D., Chemistry: Arizona State University, USA, 2015
• M.Sc., Chemistry: Indian Institute of Technology Madras, India, (2007-2009)
• B.Sc., Chemistry: Jadavpur University, India, (2004-2007)

Research Interests

• Single-molecule biophysics.
• Green chemistry and material science.
• Medicinal chemistry.
• Sustainable leather alternatives

Dr. Subhadip Senapati

Professional Experience

• Postdoctoral research: Case Western Reserve University, USA. (2015-2019)

Biography

Dr. Subhadip Senapati is a Senior Researcher at Prayoga, specializing in nanochemistry, green chemistry, and bioorganic chemistry to address industrial challenges. He completed his B.Sc. at Jadavpur University in 2007, his M.Sc. at the Indian Institute of Madras in 2009, and earned his Ph.D. from Arizona State University in 2015. His research journey began with a short-term project on medicinal chemistry at IIT Madras, where he extensively used atomic force microscopy (AFM) for structural and functional analysis of biological samples. Under the guidance of Dr. Stuart Lindsay during his Ph.D., he developed novel AFM-based biosensing techniques and engaged in projects related to organic chemistry, protein-ligand interactions, and cancer cell biology. Following his doctoral studies, Dr. Senapati pursued postdoctoral training under Dr. Paul S.-H. Park at Case Western Reserve University, focusing on the protein rhodopsin, a G-protein coupled receptor essential for vision in low-light conditions. At present, he is working on multiple thematic projects on green chemistry, sustainability, material science, and medicinal chemistry.

Ongoing Research Projects

1. Development of an alternative form of natural leather
2. Medicinal properties of anacardic acid: A single molecule study (Wellness)
3. Chemical composition of Ayurvedic medicine for Diabetes (Wellness)
4. Green synthesis of metal nanoparticles and its applications (Green Chemistry)
5. Phytochemical analysis of Rubus extract and its application (Wellness)
6. Extraction of saponin and its application (Wellness)

Representative Publication

  • Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa. S Vasudevan, S Senapati, M Pendergast, PSH Park, Nature Communications 15 (1), 1451. https://doi.org/10.1038/s41467-024-45748-4 


  • Understanding the rhodopsin worldview through atomic force microscopy (AFM): structure, stability, and activity studies S Senapati, PSH Park The Chemical Record 23 (10), e202300113. https://doi.org/10.1002/tcr.202300113 


  • Chemical education and research in India: Challenges, perspectives, and future opportunities in line with the National Education Policy 2020. S Senapati, HS Nagaraja, TN Guru Row. Journal of Chemical Education 99 (11), 3678-3686. https://doi.org/10.1021/acs.jchemed.2c00454 



  • Application of catalyst-free click reactions in attaching affinity molecules to tips of atomic force microscopy for detection of protein biomarkers S Senapati, S Manna, S Lindsay, P Zhang Langmuir 29 (47), 14622-14630. https://doi.org/10.1021/la4039667

Awards/Honours/Affiliation/Membership

1. Shortlisted for the prestigious CSIR-SPM Fellowship (India) NET 2009
2. GATE 2009 (India): All India rank: 20
3. Academic scholarship during MSc program, IIT Madras, India
4. Diversity in Science grant 2024 by Biochemical Society (UK)

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